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Quick start

Once CoSci is installed and open at http://localhost:8799, here’s the loop. Each screen maps to a stage of the research lifecycle.

1. Home — your focal point

The Home screen shows your one focal question and what needs you — the tasks waiting on your input or approval. Start here every session.

2. Capture — throw in an idea

Open Capture and drop a rough idea in plain language. Hit Incubate and CoSci turns it into ranked candidate questions. Pick the one worth pursuing.

Then, per question:

  • Run literature sweep — a real search across scientific databases.
  • Build mechanism context — pulls real protein domains + PDB structures for the entities involved.
  • Check citations — audits claims against references that actually exist.

3. Experiments — the killer test

In Experiments, lay out competing mechanisms and design the killer experiment that would distinguish them. An experiment can’t be marked Ready until it has hard kill-criteria and named artifact risks — the falsification gate.

4. Proposals / Papers — write it up

Generate 3-agent proposal or manuscript packets (draft + critic). Everything is grounded in the sources you swept and the observations you recorded.

5. Agents / Runs — see everything

The Agents screen shows every model and tool call — with provider, cache state, and online/offline badges. Nothing happens off-screen.


Want to see the entire loop run at once against real tools? Follow the worked example.